influenza A virus (IAV) in typical clinical situations, new data show.

" />
Tuesday 22 September 2020

Plain Water Better Than Hand Sanitizer for Influenza A

  • 30 September 2019
  • 13:05
  • 1 Comment
  • 559 View
  • Article Rating
Plain Water Better Than Hand Sanitizer for Influenza A
Simple handwashing — even without soap — is more effective than many hand disinfectants for killing influenza A virus (IAV) in typical clinical situations, new data show.

The researchers say the key factor that determines the effectiveness of ethanol-based disinfectants (EBDs) is whether there is wet mucus surrounding the virus. Wet mucus prevents the disinfectant from reaching the virus, which means the virus remained active after 120 seconds of EBD exposure.

By contrast, washing hands under plain water for 30 seconds inactivated the virus, regardless of whether it was initially surrounded by wet or dry mucus.

"The physical properties of mucus protect the virus from inactivation," lead researcher Ryohei Hirose, PhD, MD, a physician and molecular gastroenterologist at Kyoto Prefectural University of Medicine in Japan, said in a news release. "Until the mucus has completely dried, infectious IAV can remain on the hands and fingers, even after appropriate antiseptic hand rubbing."

 

Hirose and colleagues published their findings online September 18 in mSphere.

For the study, they first looked at the physical properties of mucus and found that ethanol travels more slowly through the thick, sticky substance than it does through saline, which has similar properties as plain water.

Next, the researchers attempted to simulate clinical situations in which healthcare professionals might transmit the virus: they collected sputum for IAV-infected patients and applied it to human fingers. After being exposed to an EBD for 2 minutes, the IAV was still active in the mucus on participants' fingertips. The virus was deactivated by 4 minutes.

If, however, the researchers allowed the mucus to fully dry on participants' hands before they used EBD, the hand sanitizer quickly inactivated the virus.

The Centers for Disease Control and Prevention and the World Health Organization recommend using disinfectants such as EBDs for 15 to 30 seconds. "However, our results suggest that this disinfection time is insufficient for the disinfection of infectious mucus of IAV-infected patients adhered to the fingers/hands and that current contact infection prevention and [antiseptic hand rubbing] regimens using EBDs are not sufficient to prevent IAV outbreaks," the researchers write.

The findings challenge those of previous studies, most of which have tested EBDs on dry mucus.

Given their results, the authors recommend actually washing hands and not simply rubbing them with hand disinfectant.

The study authors have disclosed no relevant financial relationships.

 

mSphere. Published online September 18, 2019. Full text

 

Source: Medscape

راهبر سیستم Rate News :

Send comments

Name (required)

Email (required)

Website

your comments

Fancypants
Fancypants Friday, May 1, 2020 07:31
CDC recommends washing hands with soap and water whenever possible because handwashing reduces the amounts of all types of germs and chemicals on hands. But if soap and water are not available, using a hand sanitizer with at least 60% alcohol can help you avoid getting sick and spreading germs to others. The guidance for effective handwashing and use of hand sanitizer in community settings was developed based on data from a number of studies.
URL: www.housecleaninghamiltonnz.info/